Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes

Osteoarthritis (OA) is a joint disease characterized by degeneration of the articular cartilage, subchondral bone remodeling, and secondary inflammation. It is among the top three causes of chronic disability, and currently there are no treatment options to prevent disease progression. The localized...

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Detalles Bibliográficos
Autores principales: Ruan, Merry ZC, Cerullo, Vincenzo, Cela, Racel, Clarke, Chris, Lundgren-Akerlund, Evy, Barry, Michael A, Lee, Brendan HL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008224/
https://www.ncbi.nlm.nih.gov/pubmed/27626040
http://dx.doi.org/10.1038/mtm.2016.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008224/
https://www.ncbi.nlm.nih.gov/pubmed/27626040
http://dx.doi.org/10.1038/mtm.2016.8

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