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Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes
Osteoarthritis (OA) is a joint disease characterized by degeneration of the articular cartilage, subchondral bone remodeling, and secondary inflammation. It is among the top three causes of chronic disability, and currently there are no treatment options to prevent disease progression. The localized...
Autores principales: | Ruan, Merry ZC, Cerullo, Vincenzo, Cela, Racel, Clarke, Chris, Lundgren-Akerlund, Evy, Barry, Michael A, Lee, Brendan HL |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008224/ https://www.ncbi.nlm.nih.gov/pubmed/27626040 http://dx.doi.org/10.1038/mtm.2016.8 |
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