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High-content molecular profiling of T-cell therapy in oncology

Recent clinical data have revealed the remarkable potential for T-cell-modulating agents to induce potent and durable responses in a subset of cancer patients. In this review, we discuss molecular approaches, platforms, and strategies that enable a broader interrogation of the activity of agents tha...

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Detalles Bibliográficos
Autores principales: Novosiadly, Ruslan, Kalos, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008264/
https://www.ncbi.nlm.nih.gov/pubmed/27626060
http://dx.doi.org/10.1038/mto.2016.9