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Na(+)/H(+) exchanger NHE1 regulation modulates metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer cells

In triple-negative breast cancer (TNBC), the high recurrence rate, increased invasion and aggressive metastatic formation dictate patient survival. We previously demonstrated a critical role for the Na(+)/H(+) exchanger isoform 1 (NHE1) in controlling metastasis of triple-negative cells. Here, we in...

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Detalles Bibliográficos
Autores principales: Amith, Schammim Ray, Wilkinson, Jodi Marie, Fliegel, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008271/
https://www.ncbi.nlm.nih.gov/pubmed/27049728
http://dx.doi.org/10.18632/oncotarget.8520