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Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas
Despite several molecular signatures for “lower grade diffuse gliomas” (LGG) have been identified, WHO grade still remains a cornerstone of treatment guidelines. Mitotic count bears a crucial role in its definition, although limited by the poor reproducibility of standard Hematoxylin & Eosin (H&...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008278/ https://www.ncbi.nlm.nih.gov/pubmed/27049832 http://dx.doi.org/10.18632/oncotarget.8498 |