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Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas

Despite several molecular signatures for “lower grade diffuse gliomas” (LGG) have been identified, WHO grade still remains a cornerstone of treatment guidelines. Mitotic count bears a crucial role in its definition, although limited by the poor reproducibility of standard Hematoxylin & Eosin (H&...

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Detalles Bibliográficos
Autores principales: Duregon, Eleonora, Bertero, Luca, Pittaro, Alessandra, Soffietti, Riccardo, Rudà, Roberta, Trevisan, Morena, Papotti, Mauro, Ventura, Laura, Senetta, Rebecca, Cassoni, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008278/
https://www.ncbi.nlm.nih.gov/pubmed/27049832
http://dx.doi.org/10.18632/oncotarget.8498