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Long-term prognostic implications and therapeutic target role of hexokinase II in patients with nasopharyngeal carcinoma
Tumor cells preferentially use anaerobic glycolysis rather than oxidative phosphorylation to generate energy. Hexokinase II (HK-II) is necessary for anaerobic glycolysis and displays aberrant expression in malignant cells. The current study aimed to evaluate the role of HK-II in the survival and bio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008285/ https://www.ncbi.nlm.nih.gov/pubmed/26848773 http://dx.doi.org/10.18632/oncotarget.7116 |