Metformin inhibits 17β-estradiol-induced epithelial-to-mesenchymal transition via βKlotho-related ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells

The potential role of metformin in treating endometrial cancer remains to be explored. The current study investigated the role of metformin in 17β-estradiol-induced epithelial-mesenchymal transition (EMT) in endometrial adenocarcinoma cells. We found that 17β-estradiol promoted proliferation and mig...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Qi, Shasha, Zhao, Xingbo, Li, Mingjiang, Ding, Sentai, Lu, Jiaju, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008287/
https://www.ncbi.nlm.nih.gov/pubmed/26824324
http://dx.doi.org/10.18632/oncotarget.7040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008287/
https://www.ncbi.nlm.nih.gov/pubmed/26824324
http://dx.doi.org/10.18632/oncotarget.7040

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