Cargando…
Metformin inhibits 17β-estradiol-induced epithelial-to-mesenchymal transition via βKlotho-related ERK1/2 signaling and AMPKα signaling in endometrial adenocarcinoma cells
The potential role of metformin in treating endometrial cancer remains to be explored. The current study investigated the role of metformin in 17β-estradiol-induced epithelial-mesenchymal transition (EMT) in endometrial adenocarcinoma cells. We found that 17β-estradiol promoted proliferation and mig...
Autores principales: | Liu, Zhao, Qi, Shasha, Zhao, Xingbo, Li, Mingjiang, Ding, Sentai, Lu, Jiaju, Zhang, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008287/ https://www.ncbi.nlm.nih.gov/pubmed/26824324 http://dx.doi.org/10.18632/oncotarget.7040 |
Ejemplares similares
-
βKlotho inhibits androgen/androgen receptor-associated epithelial-mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling
por: Liu, Zhao, et al.
Publicado: (2018) -
Melatonin inhibits 17β-estradiol-induced migration, invasion and epithelial-mesenchymal transition in normal and endometriotic endometrial epithelial cells
por: Qi, Shasha, et al.
Publicado: (2018) -
βKlotho Inhibits Cell Proliferation by Downregulating ELK4 and Predicts Favorable Prognosis in Prostate Cancer
por: Mao, Changlin, et al.
Publicado: (2021) -
Estradiol-17β-Induced Changes in the Porcine Endometrial Transcriptome In Vivo
por: Kaczynski, Piotr, et al.
Publicado: (2020) -
Crosstalk between 17β-Estradiol and TGF-β Signaling Modulates Glioblastoma Progression
por: Hernández-Vega, Ana M., et al.
Publicado: (2021)