Molecular spectrum of TP53 mutations in plasma cell dyscrasias by next generation sequencing: an Italian cohort study and overview of the literature

The prevalence of TP53 mutations greatly varies between tumor types; in multiple myeloma (MM) they were rarely detected at presentation, while increased frequency was reported with disease progression. Using next-generation sequencing, we analyzed TP53 exons 4-9 in a large representative cohort comp...

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Detalles Bibliográficos
Autores principales: Lionetti, Marta, Barbieri, Marzia, Manzoni, Martina, Fabris, Sonia, Bandini, Cecilia, Todoerti, Katia, Nozza, Filomena, Rossi, Davide, Musto, Pellegrino, Baldini, Luca, Neri, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008290/
https://www.ncbi.nlm.nih.gov/pubmed/26870891
http://dx.doi.org/10.18632/oncotarget.7241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008290/
https://www.ncbi.nlm.nih.gov/pubmed/26870891
http://dx.doi.org/10.18632/oncotarget.7241

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