The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation

Renal cell carcinoma (RCC) is the most common urological cancer with steadily increasing incidence. A series of tumor suppressor genes (TSGs) have been identified methylated in RCC as potential epigenetic biomarkers. We identified a 1p36.3 TSG candidate CHD5 as a methylated target in RCC through epi...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Zhenfang, Li, Lili, Huang, Xin, Jin, Jie, Huang, Suming, Zhang, Qian, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008310/
https://www.ncbi.nlm.nih.gov/pubmed/26943038
http://dx.doi.org/10.18632/oncotarget.7822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008310/
https://www.ncbi.nlm.nih.gov/pubmed/26943038
http://dx.doi.org/10.18632/oncotarget.7822

Ejemplares similares