Screening of candidate G-quadruplex ligands for the human c-KIT promotorial region and their effects in multiple in-vitro models

Stabilization of G-quadruplex (G4) structures in promoters is a novel promising strategy to regulate gene expression at transcriptional and translational levels. c-KIT proto-oncogene encodes for a tyrosine kinase receptor. It is involved in several physiological processes, but it is also dysregulate...

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Detalles Bibliográficos
Autores principales: Zorzan, Eleonora, Ros, Silvia Da, Musetti, Caterina, Shahidian, Lara Zorro, Ramos Coelho, Nuno Filipe, Bonsembiante, Federico, Létard, Sébastien, Gelain, Maria Elena, Palumbo, Manlio, Dubreuil, Patrice, Giantin, Mery, Sissi, Claudia, Dacasto, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008313/
https://www.ncbi.nlm.nih.gov/pubmed/26942875
http://dx.doi.org/10.18632/oncotarget.7808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008313/
https://www.ncbi.nlm.nih.gov/pubmed/26942875
http://dx.doi.org/10.18632/oncotarget.7808

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