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Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

This retrospective study aimed to investigate the role that an RNA-binding protein, HuR, plays in the response of high-grade serous ovarian tumors to chemotherapeutics. We immunohistochemically stained sections of 31 surgically-debulked chemo-naïve ovarian tumors for HuR and scored the degree of HuR...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Hung, Peng, Weidan, Furuuchi, Narumi, DuHadaway, James B., Jimbo, Masaya, Pirritano, Andrea, Dunton, Charles J., Daum, Gary S., Leiby, Benjamin E., Brody, Jonathan R., Sawicki, Janet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008325/
https://www.ncbi.nlm.nih.gov/pubmed/26943573
http://dx.doi.org/10.18632/oncotarget.7840