Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma

Ion channels play a major factor in maintaining cellular homeostasis but very little is known about the role of these proteins in cancer biology. In this work we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a can...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez-Neut, Mathew, Haar, Lauren, Rao, Vidhya, Santha, Sreevidya, Lansu, Katherine, Rana, Basabi, Jones, Walter K., Gentile, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008339/
https://www.ncbi.nlm.nih.gov/pubmed/26942884
http://dx.doi.org/10.18632/oncotarget.7831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008339/
https://www.ncbi.nlm.nih.gov/pubmed/26942884
http://dx.doi.org/10.18632/oncotarget.7831

Ejemplares similares