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Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
Ion channels play a major factor in maintaining cellular homeostasis but very little is known about the role of these proteins in cancer biology. In this work we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a can...
Autores principales: | Perez-Neut, Mathew, Haar, Lauren, Rao, Vidhya, Santha, Sreevidya, Lansu, Katherine, Rana, Basabi, Jones, Walter K., Gentile, Saverio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008339/ https://www.ncbi.nlm.nih.gov/pubmed/26942884 http://dx.doi.org/10.18632/oncotarget.7831 |
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