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Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation

Castration resistance is a serious problem facing clinical treatment of prostate cancer (PCa). The underlying molecular mechanisms of acquired proliferation ability of tumor cells upon androgen deprivation are largely undetermined. In the present study, we identified that ubiquitin specific peptidas...

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Detalles Bibliográficos
Autores principales: Huang, Yi, Pan, Xiu-Wu, Li, Lin, Chen, Lu, Liu, Xi, Lu, Jian-Lei, Zhu, Xiao-Mei, Huang, Hai, Yang, Qi-Wei, Ye, Jian-Qing, Gan, Si-Shun, Wang, Lin-Hui, Hong, Yi, Xu, Dan-Feng, Cui, Xin-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008341/
https://www.ncbi.nlm.nih.gov/pubmed/26959883
http://dx.doi.org/10.18632/oncotarget.7882