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Specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4 are non-oncogene addiction genes in cancer cells

Specificity protein (Sp) transcription factor (TF) Sp1 is overexpressed in multiple tumors and is a negative prognostic factor for patient survival. Sp1 and also Sp3 and Sp4 are highly expressed in cancer cells and in this study, we have used results of RNA interference (RNAi) to show that the three...

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Detalles Bibliográficos
Autores principales: Hedrick, Erik, Cheng, Yating, Jin, Un-Ho, Kim, Kyounghyun, Safe, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008359/
https://www.ncbi.nlm.nih.gov/pubmed/26967243
http://dx.doi.org/10.18632/oncotarget.7925