In vitro and in vivo anti-tumor activity of CoQ(0) against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways

Coenzyme Q(0) (CoQ(0), 2,3-dimethoxy-5-methyl-1,4-benzoquinone), a novel quinone derivative, has been shown to modulate cellular redox balance. However, effect of this compound on melanoma remains unclear. This study examined the in vitro or in vivo anti-tumor, apoptosis, and anti-metastasis activit...

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Detalles Bibliográficos
Autores principales: Hseu, You-Cheng, Thiyagarajan, Varadharajan, Tsou, Hsiao-Tung, Lin, Kai-Yuan, Chen, Hui-Jye, Lin, Chung-Ming, Liao, Jiuun-Wang, Yang, Hsin-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008369/
https://www.ncbi.nlm.nih.gov/pubmed/26968952
http://dx.doi.org/10.18632/oncotarget.7983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008369/
https://www.ncbi.nlm.nih.gov/pubmed/26968952
http://dx.doi.org/10.18632/oncotarget.7983

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