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In vitro and in vivo anti-tumor activity of CoQ(0) against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways
Coenzyme Q(0) (CoQ(0), 2,3-dimethoxy-5-methyl-1,4-benzoquinone), a novel quinone derivative, has been shown to modulate cellular redox balance. However, effect of this compound on melanoma remains unclear. This study examined the in vitro or in vivo anti-tumor, apoptosis, and anti-metastasis activit...
Autores principales: | Hseu, You-Cheng, Thiyagarajan, Varadharajan, Tsou, Hsiao-Tung, Lin, Kai-Yuan, Chen, Hui-Jye, Lin, Chung-Ming, Liao, Jiuun-Wang, Yang, Hsin-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008369/ https://www.ncbi.nlm.nih.gov/pubmed/26968952 http://dx.doi.org/10.18632/oncotarget.7983 |
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