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Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas

PIWI pathway proteins are expressed during spermatogenesis where they play a key role in germ cell development. Epigenetic loss of PIWI proteins expression was previously demonstrated in testicular germ cell tumors (TGCTs), implying their involvement in TGCT development. In this work, apart from stu...

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Detalles Bibliográficos
Autores principales: Gainetdinov, Ildar V., Kondratieva, Sofia A., Skvortsova, Yulia V., Zinovyeva, Marina V., Stukacheva, Elena A., Klimov, Alexey, Tryakin, Alexey A., Azhikina, Tatyana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008371/
https://www.ncbi.nlm.nih.gov/pubmed/26843623
http://dx.doi.org/10.18632/oncotarget.7074