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Distinguishing epigenetic features of preneoplastic testis tissues adjacent to seminomas and nonseminomas
PIWI pathway proteins are expressed during spermatogenesis where they play a key role in germ cell development. Epigenetic loss of PIWI proteins expression was previously demonstrated in testicular germ cell tumors (TGCTs), implying their involvement in TGCT development. In this work, apart from stu...
Autores principales: | Gainetdinov, Ildar V., Kondratieva, Sofia A., Skvortsova, Yulia V., Zinovyeva, Marina V., Stukacheva, Elena A., Klimov, Alexey, Tryakin, Alexey A., Azhikina, Tatyana L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008371/ https://www.ncbi.nlm.nih.gov/pubmed/26843623 http://dx.doi.org/10.18632/oncotarget.7074 |
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