Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance

S100P belongs to the S100 family of calcium-binding proteins regulating diverse cellular processes. Certain S100 family members (S100A4 and S100B) are associated with cancer and used as biomarkers of metastatic phenotype. Also S100P is abnormally expressed in tumors and implicated in migration-invas...

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Detalles Bibliográficos
Autores principales: Gibadulinova, Adriana, Pastorek, Michal, Filipcik, Pavel, Radvak, Peter, Csaderova, Lucia, Vojtesek, Borivoj, Pastorekova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008377/
https://www.ncbi.nlm.nih.gov/pubmed/26967060
http://dx.doi.org/10.18632/oncotarget.7999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008377/
https://www.ncbi.nlm.nih.gov/pubmed/26967060
http://dx.doi.org/10.18632/oncotarget.7999

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