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Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance
S100P belongs to the S100 family of calcium-binding proteins regulating diverse cellular processes. Certain S100 family members (S100A4 and S100B) are associated with cancer and used as biomarkers of metastatic phenotype. Also S100P is abnormally expressed in tumors and implicated in migration-invas...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008377/ https://www.ncbi.nlm.nih.gov/pubmed/26967060 http://dx.doi.org/10.18632/oncotarget.7999 |