Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms

Lysine acetylation has been reported to involve in the pathogenesis of multiple diseases including cancer. In our screening study to identify natural compounds with lysine acetyltransferase inhibitor (KATi) activity, oridonin was found to possess acetyltransferase-inhibitory effects on multiple acet...

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Detalles Bibliográficos
Autores principales: Shi, Min, Lu, Xiao-Jie, Zhang, Juan, Diao, Hua, Li, Guangming, Xu, Ling, Wang, Ting, Wei, Jue, Meng, Wenying, Ma, Jia-Li, Yu, Heguo, Wang, Yu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008386/
https://www.ncbi.nlm.nih.gov/pubmed/26980707
http://dx.doi.org/10.18632/oncotarget.8033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008386/
https://www.ncbi.nlm.nih.gov/pubmed/26980707
http://dx.doi.org/10.18632/oncotarget.8033

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