Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer

The small GTPase Rab25 has been functionally linked to tumour progression and aggressiveness in ovarian cancer and promotes invasion in three-dimensional environments. This type of migration has been shown to require the expression of the hypoxia-inducible factor 1 alpha (HIF-1α). In this report we...

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Detalles Bibliográficos
Autores principales: Gomez-Roman, Natividad, Sahasrabudhe, Neha Mohan, McGregor, Fiona, Chalmers, Anthony J., Cassidy, Jim, Plumb, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008389/
https://www.ncbi.nlm.nih.gov/pubmed/26967059
http://dx.doi.org/10.18632/oncotarget.7998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008389/
https://www.ncbi.nlm.nih.gov/pubmed/26967059
http://dx.doi.org/10.18632/oncotarget.7998

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