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Challenges in detecting pre-malignant pancreatic lesions during acute pancreatitis using a serum microRNA assay: a study based on Kras(G12D) transgenic mice

Caerulein-induced acute pancreatitis accelerates the progression of pancreatic intraepithelial neoplasia (PanIN) lesions in a pancreas-specific Kras(G12D) mouse model. The purpose of this study was to explore whether serum microRNAs (miRNAs) can serve as sensitive biomarkers to detect occult PanIN i...

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Detalles Bibliográficos
Autores principales: Hong, Xiafei, Zhang, Jie, Wu, Qiao, Wang, Wenze, Ye, Adam Yongxin, Song, Wei, Dai, Hongmei, Wang, Xianze, Wu, Fan, You, Lei, Wu, Wenming, Zhao, Yupei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008393/
https://www.ncbi.nlm.nih.gov/pubmed/27009811
http://dx.doi.org/10.18632/oncotarget.8148