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Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide, which highlights the need of innovative therapeutic options. Although targeted therapies can be successfully used in a subset of patients with lung adenocarcinomas (ADC), they are not appropriate for patients...

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Detalles Bibliográficos
Autores principales: Villalba, Maria, Diaz-Lagares, Angel, Redrado, Miriam, de Aberasturi, Arrate L., Segura, Victor, Bodegas, Maria Elena, Pajares, Maria J., Pio, Ruben, Freire, Javier, Gomez-Roman, Javier, Montuenga, Luis M., Esteller, Manel, Sandoval, Juan, Calvo, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008398/
https://www.ncbi.nlm.nih.gov/pubmed/26989022
http://dx.doi.org/10.18632/oncotarget.8045