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ATP7B expression confers multidrug resistance through drug sequestration

We previously reported that ATP7B is involved in cisplatin resistance and ATP7A confers multidrug resistance (MDR) in cancer cells. In this study, we show that ATP7B expressing cells also are resistant to doxorubicin, SN-38, etoposide, and paclitaxel as well as cisplatin. In ATP7B expressing cells,...

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Detalles Bibliográficos
Autores principales: Moinuddin, F M, Shinsato, Yoshinari, Komatsu, Masaharu, Mitsuo, Ryoichi, Minami, Kentaro, Yamamoto, Masatatsu, Kawahara, Kohich, Hirano, Hirofumi, Arita, Kazunori, Furukawa, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008400/
https://www.ncbi.nlm.nih.gov/pubmed/26988911
http://dx.doi.org/10.18632/oncotarget.8059