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Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters

Mammalian transcriptomes are complex and formed by extensive promoter activity. In addition, gene promoters are largely divergent and initiate transcription of reverse-oriented promoter upstream transcripts (PROMPTs). Although PROMPTs are commonly terminated early, influenced by polyadenylation site...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Pai, Athma A., Herudek, Jan, Lubas, Michal, Meola, Nicola, Järvelin, Aino I., Andersson, Robin, Pelechano, Vicent, Steinmetz, Lars M., Heick Jensen, Torben, Sandelin, Albin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008441/
https://www.ncbi.nlm.nih.gov/pubmed/27455346
http://dx.doi.org/10.1038/ng.3616