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Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Mammalian transcriptomes are complex and formed by extensive promoter activity. In addition, gene promoters are largely divergent and initiate transcription of reverse-oriented promoter upstream transcripts (PROMPTs). Although PROMPTs are commonly terminated early, influenced by polyadenylation site...
Autores principales: | Chen, Yun, Pai, Athma A., Herudek, Jan, Lubas, Michal, Meola, Nicola, Järvelin, Aino I., Andersson, Robin, Pelechano, Vicent, Steinmetz, Lars M., Heick Jensen, Torben, Sandelin, Albin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008441/ https://www.ncbi.nlm.nih.gov/pubmed/27455346 http://dx.doi.org/10.1038/ng.3616 |
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