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Real-time selective sequencing using nanopore technology

The Oxford Nanopore MinION sequences DNA by sensing changes in electrical current flow in real-time as molecules traverse nanopores. Optionally, the voltage across specific nanopores can be reversed, ejecting the DNA molecule. This enables “Read Until”, the selection of specific DNA molecules for se...

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Detalles Bibliográficos
Autores principales: Loose, Matthew, Malla, Sunir, Stout, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008457/
https://www.ncbi.nlm.nih.gov/pubmed/27454285
http://dx.doi.org/10.1038/nmeth.3930