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Lysine and the Na(+)/K(+) Selectivity in Mammalian Voltage-Gated Sodium Channels

Voltage-gated sodium (Na(v)) channels are critical in the generation and transmission of neuronal signals in mammals. The crystal structures of several prokaryotic Na(v) channels determined in recent years inspire the mechanistic studies on their selection upon the permeable cations (especially betw...

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Detalles Bibliográficos
Autores principales: Li, Yang, Liu, Huihui, Xia, Mengdie, Gong, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008630/
https://www.ncbi.nlm.nih.gov/pubmed/27584582
http://dx.doi.org/10.1371/journal.pone.0162413