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Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised

BACKGROUND: The over-expression of transforming growth factor β-1(TGF-β1) has been reported to cause hydrocephalus, glia activation, and vascular amyloidβ (Aβ) deposition in mouse brains. Since these phenomena partially mimic the cerebral amyloid angiopathy (CAA) concomitant to Alzheimer's dise...

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Detalles Bibliográficos
Autores principales: Lacombe, Pierre, Mathews, Paul M, Schmidt, Stephen D, Breidert, Tilo, Heneka, Michael T, Landreth, Gary E, Feinstein, Douglas L, Galea, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC500868/
https://www.ncbi.nlm.nih.gov/pubmed/15285804
http://dx.doi.org/10.1186/1742-2094-1-11