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DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment
Male mammals produce sperm for most of postnatal life and therefore require a robust germ line stem cell system, with precise balance between self-renewal and differentiation. Prior work established doublesex- and mab-3-related transcription factor 1 (Dmrt1) as a conserved transcriptional regulator...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008761/ https://www.ncbi.nlm.nih.gov/pubmed/27583450 http://dx.doi.org/10.1371/journal.pgen.1006293 |