Cargando…
DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment
Male mammals produce sperm for most of postnatal life and therefore require a robust germ line stem cell system, with precise balance between self-renewal and differentiation. Prior work established doublesex- and mab-3-related transcription factor 1 (Dmrt1) as a conserved transcriptional regulator...
Autores principales: | Zhang, Teng, Oatley, Jon, Bardwell, Vivian J., Zarkower, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008761/ https://www.ncbi.nlm.nih.gov/pubmed/27583450 http://dx.doi.org/10.1371/journal.pgen.1006293 |
Ejemplares similares
-
DMRT1 prevents female reprogramming in the postnatal mammalian testis
por: Matson, Clinton K., et al.
Publicado: (2011) -
Glycolysis-Optimized Conditions Enhance Maintenance of Regenerative Integrity in Mouse Spermatogonial Stem Cells during Long-Term Culture
por: Helsel, Aileen R., et al.
Publicado: (2017) -
The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming
por: Lindeman, Robin E, et al.
Publicado: (2021) -
A regulatory role for CHD4 in maintenance of the spermatogonial stem cell pool
por: Cafe, Shenae L., et al.
Publicado: (2021) -
MicroRNA‐224 regulates self‐renewal of mouse spermatogonial stem cells via targeting DMRT1
por: Cui, Na, et al.
Publicado: (2016)