Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity

VWF is extensively glycosylated with biantennary core fucosylated glycans. Most N-linked and O-linked glycans on VWF are sialylated. FVIII is also glycosylated, with a glycan structure similar to that of VWF. ST3GAL sialyltransferases catalyze the transfer of sialic acids in the α2,3 linkage to term...

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Detalles Bibliográficos
Autores principales: Song, Jaewoo, Xue, Cheng, Preisser, John S., Cramer, Drake W., Houck, Katie L., Liu, Guo, Folsom, Aaron R., Couper, David, Yu, Fuli, Dong, Jing-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008807/
https://www.ncbi.nlm.nih.gov/pubmed/27584569
http://dx.doi.org/10.1371/journal.pone.0160757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008807/
https://www.ncbi.nlm.nih.gov/pubmed/27584569
http://dx.doi.org/10.1371/journal.pone.0160757

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