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D1398G Variant of MET Is Associated with Impaired Signaling of Hepatocyte Growth Factor in Alveolar Epithelial Cells and Lung Fibroblasts

Pulmonary fibrosis represents the terminal stage of a diverse group of lung diseases including scleroderma associated interstitial lung disease. The molecular mechanisms underlying the pathogenesis of lung fibrosis are not well understood and there is a great need for more effective treatment for th...

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Detalles Bibliográficos
Autores principales: Atanelishvili, Ilia, Shirai, Yuichiro, Akter, Tanjina, Noguchi, Atsushi, Ash, Kurt T., Misra, Suniti, Ghatak, Sibnath, Silver, Richard M., Bogatkevich, Galina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008815/
https://www.ncbi.nlm.nih.gov/pubmed/27584154
http://dx.doi.org/10.1371/journal.pone.0162357