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Tension Recovery following Ramp-Shaped Release in High-Ca and Low-Ca Rigor Muscle Fibers: Evidence for the Dynamic State of AMADP Myosin Heads in the Absence of ATP

During muscle contraction, myosin heads (M) bound to actin (A) perform power stroke associated with reaction, AMADPPi → AM + ADP + Pi. In this scheme, A • M is believed to be a high-affinity complex after removal of ATP. Biochemical studies on extracted protein samples show that, in the AM complex,...

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Detalles Bibliográficos
Autores principales: Sugi, Haruo, Yamaguchi, Maki, Ohno, Tetsuo, Kobayashi, Takakazu, Chaen, Shigeru, Okuyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008834/
https://www.ncbi.nlm.nih.gov/pubmed/27583360
http://dx.doi.org/10.1371/journal.pone.0162003