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Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression

The variegated expression of murine Ly49 loci has been associated with the probabilistic behavior of an upstream promoter active in immature cells, the Pro1 element. However, recent data suggests that Pro1 may be active in mature NK cells and function as an enhancer element. To directly assess if Pr...

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Detalles Bibliográficos
Autores principales: McCullen, Matthew V., Li, Hongchuan, Cam, Maggie, Sen, Shurjo K., McVicar, Daniel W., Anderson, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008998/
https://www.ncbi.nlm.nih.gov/pubmed/27467282
http://dx.doi.org/10.1038/gene.2016.31