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Blockade of Apoptosis Signal-Regulating Kinase 1 Attenuates Matrix Metalloproteinase 9 Activity in Brain Endothelial Cells and the Subsequent Apoptosis in Neurons after Ischemic Injury

Conditions of increased oxidative stress including cerebral ischemia can lead to blood–brain barrier dysfunction via matrix metalloproteinase (MMP). It is known that MMP-9 in particular is released from brain endothelial cells is involved in the neuronal cell death that occurs after cerebral ischemi...

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Detalles Bibliográficos
Autores principales: Cheon, So Y., Cho, Kyoung J., Kim, So Y., Kam, Eun H., Lee, Jong E., Koo, Bon-Nyeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009117/
https://www.ncbi.nlm.nih.gov/pubmed/27642277
http://dx.doi.org/10.3389/fncel.2016.00213