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Astragaloside IV ameliorates renal injury in db/db mice

Diabetic nephropathy is a lethal complication of diabetes mellitus and a major type of chronic kidney disease. Dysregulation of the Akt pathway and its downstream cascades, including mTOR, NFκB, and Erk1/2, play a critical role in the development of diabetic nephropathy. Astragaloside IV is a major...

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Detalles Bibliográficos
Autores principales: Sun, Huili, Wang, Wenjing, Han, Pengxun, Shao, Mumin, Song, Gaofeng, Du, Heng, Yi, Tiegang, Li, Shunmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009300/
https://www.ncbi.nlm.nih.gov/pubmed/27585918
http://dx.doi.org/10.1038/srep32545