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Astragaloside IV ameliorates renal injury in db/db mice
Diabetic nephropathy is a lethal complication of diabetes mellitus and a major type of chronic kidney disease. Dysregulation of the Akt pathway and its downstream cascades, including mTOR, NFκB, and Erk1/2, play a critical role in the development of diabetic nephropathy. Astragaloside IV is a major...
Autores principales: | Sun, Huili, Wang, Wenjing, Han, Pengxun, Shao, Mumin, Song, Gaofeng, Du, Heng, Yi, Tiegang, Li, Shunmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009300/ https://www.ncbi.nlm.nih.gov/pubmed/27585918 http://dx.doi.org/10.1038/srep32545 |
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