Association between Oxidative DNA Damage and Risk of Colorectal Cancer: Sensitive Determination of Urinary 8-Hydroxy-2′-deoxyguanosine by UPLC-MS/MS Analysis

Oxidative DNA damage plays crucial roles in the pathogenesis of numerous diseases including cancer. 8-hydroxy-2′-deoxyguanosine (8-OHdG) is the most representative product of oxidative modifications of DNA, and urinary 8-OHdG is potentially the best non-invasive biomarker of oxidative damage to DNA....

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Detalles Bibliográficos
Autores principales: Guo, Cheng, Li, Xiaofen, Wang, Rong, Yu, Jiekai, Ye, Minfeng, Mao, Lingna, Zhang, Suzhan, Zheng, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009303/
https://www.ncbi.nlm.nih.gov/pubmed/27585556
http://dx.doi.org/10.1038/srep32581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009303/
https://www.ncbi.nlm.nih.gov/pubmed/27585556
http://dx.doi.org/10.1038/srep32581

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