SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation

Like most other types of cancer cells, leukaemia cells undergo metabolic reprogramming to support rapid proliferation through enhancing biosynthetic processes. Pentose phosphate pathway (PPP) plays a pivotal role in meeting the anabolic demands for cancer cells. However, the molecular mechanism by w...

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Detalles Bibliográficos
Autores principales: Xu, Shuang-Nian, Wang, Tian-Shi, Li, Xi, Wang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009355/
https://www.ncbi.nlm.nih.gov/pubmed/27586085
http://dx.doi.org/10.1038/srep32734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009355/
https://www.ncbi.nlm.nih.gov/pubmed/27586085
http://dx.doi.org/10.1038/srep32734

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