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Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells

Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including...

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Detalles Bibliográficos
Autores principales: Morhayim, Jess, van de Peppel, Jeroen, Braakman, Eric, Rombouts, Elwin W. J. C., ter Borg, Mariette N. D., Dudakovic, Amel, Chiba, Hideki, van der Eerden, Bram C. J., Raaijmakers, Marc H., van Wijnen, Andre J., Cornelissen, Jan J., van Leeuwen, Johannes P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009378/
https://www.ncbi.nlm.nih.gov/pubmed/27585950
http://dx.doi.org/10.1038/srep32034