Replication Timing of Human Telomeres is Conserved during Immortalization and Influenced by Respective Subtelomeres

Telomeres are specific structures that protect chromosome ends and act as a biological clock, preventing normal cells from replicating indefinitely. Mammalian telomeres are replicated throughout S-phase in a predetermined order. However, the mechanism of this regulation is still unknown. We wished t...

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Detalles Bibliográficos
Autores principales: Piqueret-Stephan, Laure, Ricoul, Michelle, Hempel, William M., Sabatier, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009427/
https://www.ncbi.nlm.nih.gov/pubmed/27587191
http://dx.doi.org/10.1038/srep32510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009427/
https://www.ncbi.nlm.nih.gov/pubmed/27587191
http://dx.doi.org/10.1038/srep32510

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