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Replication Timing of Human Telomeres is Conserved during Immortalization and Influenced by Respective Subtelomeres
Telomeres are specific structures that protect chromosome ends and act as a biological clock, preventing normal cells from replicating indefinitely. Mammalian telomeres are replicated throughout S-phase in a predetermined order. However, the mechanism of this regulation is still unknown. We wished t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009427/ https://www.ncbi.nlm.nih.gov/pubmed/27587191 http://dx.doi.org/10.1038/srep32510 |