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Identification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cells
Chronic myeloid leukemia (CML) is maintained by leukemic stem cells (LSCs) which are resistant to the existing TKI therapy. Hence a better understanding of the CML LSCs is necessary to eradicate these cells and achieve complete cure. Using the miRNA-gene interaction networks from the CML lin(−) cell...
Autores principales: | Agatheeswaran, S., Pattnayak, N. C., Chakraborty, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009428/ https://www.ncbi.nlm.nih.gov/pubmed/27586591 http://dx.doi.org/10.1038/srep32493 |
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