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Investigating cellular network heterogeneity and modularity in cancer: a network entropy and unbalanced motif approach

BACKGROUND: Cancer is increasingly recognized as a cellular system phenomenon that is attributed to the accumulation of genetic or epigenetic alterations leading to the perturbation of the molecular network architecture. Elucidation of network properties that can characterize tumor initiation and pr...

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Detalles Bibliográficos
Autores principales: Cheng, Feixiong, Liu, Chuang, Shen, Bairong, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009528/
https://www.ncbi.nlm.nih.gov/pubmed/27585651
http://dx.doi.org/10.1186/s12918-016-0309-9