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Investigating cellular network heterogeneity and modularity in cancer: a network entropy and unbalanced motif approach
BACKGROUND: Cancer is increasingly recognized as a cellular system phenomenon that is attributed to the accumulation of genetic or epigenetic alterations leading to the perturbation of the molecular network architecture. Elucidation of network properties that can characterize tumor initiation and pr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009528/ https://www.ncbi.nlm.nih.gov/pubmed/27585651 http://dx.doi.org/10.1186/s12918-016-0309-9 |