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Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of α5β1 and αVβ3 integrins

BACKGROUND: The pro-inflammatory cytokine, tumor necrosis factor-α (TNF-α), is expressed in ischemic tissue and is known to modulate angiogenesis; however, the role of the two distinct TNF-α receptors, TNFR1 and TNFR2, in mediating angiogenic signaling after cerebral ischemic stroke is relatively un...

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Detalles Bibliográficos
Autores principales: Huang, Heng, Huang, Qijuan, Wang, Fuxin, Milner, Richard, Li, Longxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009537/
https://www.ncbi.nlm.nih.gov/pubmed/27586239
http://dx.doi.org/10.1186/s12974-016-0697-1